IARPA extends support to Signature Science’s development of a laboratory-based model to predict the evolution...

AUSTIN, TEXAS – May 18, 2021– The Intelligence Advanced Research Projects Activity (IARPA) has awarded a second phase contract extension to Signature Science, LLC to further the development of a laboratory-based model of viral evolution of pandemic viruses. Signature Science engineered non-replication competent SARS-CoV-2 vectors as proof-of-concept in the initial... MORE
Horizon Newsletter Banner. Photo of person at a laptop with cat in their lap. Text reads "February 2021"

Horizon: Signature Science to Attend Virtual 73rd AAFS

AAFS – February 16–19. The 73rd Annual American Academy of Forensic Sciences meeting has gone virtual! The breadth and depth of the latest in forensic science will be available to you from the comfort of your home and will remain online for a full 90 days. We’re excited to be contributing... MORE
Technician working on Illumina iScan with text "Horizon: November 2020"

Horizon: Committed to Cooperation

The scientists at the Center for Advanced Genomics know that the best outcomes result from collaboration, and that’s why we, in partnership with Sam Houston State University, are so excited to join the Center for Advanced Research in Forensic Science (CARFS) as an industrial member. CARFS is an Industry University Cooperative Research... MORE
Models of protein and DNA with text "DNA + Protein from Individual Fingerprints"

Fractionation of DNA and Protein from Individual Latent Fingerprints for Forensic Analysis

Abstract: Human touch samples represent a significant portion of forensic DNA casework. Yet, the generally low abundance of genetic material combined with the predominantly extracellular nature of DNA in these samples makes DNA-based forensic analysis exceptionally challenging. Human proteins present in these same touch samples offer an abundant and environmentally-robust alternative.... MORE
Stylized DNA helix with text "Signature Science's Krista Ternus Co-Authors Paper Published in PLOS"

Synthetic DNA and Biosecurity: Nuances of Predicting Pathogenicity and the Impetus for Novel Computational Approaches...

Dr. Krista Ternus worked with colleagues from Rice University and Texas A&M Health Science Center to author "Synthetic DNA and biosecurity: Nuances of predicting pathogenicity and the impetus for novel computational approaches for screening oligonucleotides." Overview: DNA synthesis technologies are enabling rapid advancements in the field of synthetic biology, which... MORE
Image of burning minivan over historical image of Wall Street bombing

New Methods, Same Motives: The IED Threat Requires a Resolute Response

THE EVOLVING THREAT The defeat of improvised explosive devices (IEDs) is, and has always been, a complex and constantly changing problem set. While the designs and methods used to build and deploy bombs have evolved, the desire of individuals and organizations to cause harm using IEDs has been constant, and... MORE