About Signature Science
We serve government and commercial clients through a wide array of technical offerings that combine scientific rigor with proven quality assurance. Our expertise enhances the credibility and defensibility of government programs that provide for National Security, Public Safety and Security, and Health Security.
We Solve Problems Using Applied Science and Technology
Across many disciplines, our project teams are addressing some of the toughest challenges facing our local communities, our nation, and our world.
Join Our Team
We’re hiring
A Compelling Work Environment and Culture
Signature Science employees benefit from a compelling work environment and corporate culture that are shaped by our pursuit of scientific innovation and service to our clients’ vital missions.
Tackling the Toughest Scientific Problems
We bring together the brightest minds from across the scientific disciplines to apply high-quality analysis and technical skills to meet new and developing challenges. Check our current openings to see where you fit.
News
Here’s what’s happening at Signature Science lately.
Horizon Newsletter – February 2026
We’re gearing up for another ASCLD Symposium and are excited to be part of 2026’s packed agenda! We’re hosting two plenary talks and one deep dive session. Scroll for a preview of SigSci Forensics on the agenda. Dates & Times TBA! View … MORE
Abstract: Accurate assessment of low-dose neutron radiation exposure remains a central challenge in biodosimetry, particularly for applications requiring non-invasive sample types such as skin. Here, we characterized the transcriptional response of a three-dimensional in vitro human skin model (EpiDermFT) to neutron irradiation at … MORE
Dr. Ben H. Thacker Joins Signature Science’s Managers Committee
Thacker serves as Chief Operating Officer of Southwest Research Institute. AUSTIN, TX – February 10, 2026 – Signature Science, LLC is pleased to announce the addition of Dr. Ben H. Thacker, P.E. to its Managers Committee following his appointment as Southwest … MORE
SigSci Products
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