About Signature Science

We serve government and commercial clients through a wide array of technical offerings that combine scientific rigor with proven quality assurance. Our expertise enhances the credibility and defensibility of government programs that provide for our national and homeland security.

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We Solve Problems Using Applied Science and Technology

Across many disciplines, our project teams are addressing some of the toughest challenges facing our nation and communities.

Join Our Team

We’re hiring

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A Compelling Work Environment and Culture

Signature Science employees benefit from a compelling work environment and corporate culture that are shaped by our pursuit of scientific innovation and service to our clients’ national security, criminal justice, and public health missions.

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Tackling the Toughest Scientific Problems

We bring together the brightest minds from across the scientific disciplines to apply high-quality analysis and technical skills to meet national security and law enforcement challenges. Check our current openings to see where you fit.


Here’s what’s happening at Signature Science lately.

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Signature Science Selected to Validate RNA Virus Detection Workflow for the Centers for Disease Control and Prevention Laboratory Response Network

Award continues CDC-funded development of standardized protocols for rapid, accurate detection of RNA viruses using the Oxford Nanopore MinION AUSTIN, TEXAS – Nov. 22, 2022– The Centers for Disease Control and Prevention (CDC) has selected Signature Science, LLC to validate an … MORE

Forecasting Influenza-Like Illness (ILI) during the COVID-19 Pandemic

Abstract Near-term probabilistic forecasts for infectious diseases such as COVID-19 and influenza play an important role in public health communication and policymaking. From 2013-2019, the FluSight challenge run by the Centers for Disease Control and Prevention invited researchers to develop and … MORE

Internal Validation of the ForenSeq Kintelligence Kit for Application to Forensic Genetic Genealogy

Abstract Forensic Genetic Genealogy (FGG) requires high density single nucleotide polymorphism (SNP) profiles to infer distant relationships. The ForenSeq Kintelligence kit is a recently developed method targeting approximately 10,000 SNPs that were selected to be compatible with genetic genealogy databases, while … MORE

SigSci Products

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