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About Signature Science

We serve government and commercial clients through a wide array of technical offerings that combine scientific rigor with proven quality assurance. Our expertise enhances the credibility and defensibility of government programs that provide for National Security, Public Safety and Security, and Health Security.

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We Solve Problems Using Applied Science and Technology

Across many disciplines, our project teams are addressing some of the toughest challenges facing our local communities, our nation, and our world.

National Security
Public Safety and Security
Health Security

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A Compelling Work Environment and Culture

Signature Science employees benefit from a compelling work environment and corporate culture that are shaped by our pursuit of scientific innovation and service to our clients’ vital missions.

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Tackling the Toughest Scientific Problems

We bring together the brightest minds from across the scientific disciplines to apply high-quality analysis and technical skills to meet new and developing challenges. Check our current openings to see where you fit.

News

Here’s what’s happening at Signature Science lately.

Published in “FSI Genetics”: Advancing forensic SNP typing: Insights from an interlaboratory study of the FORCE panel

Abstract: This study evaluated the ability to produce FORensic Capture Enrichment (FORCE) genotypes using amplicon-based and capture-based enrichment assays. The FORCE panel is a standardized set of single nucleotide polymorphism (SNP) markers developed for forensic applications. Twelve DNA samples were … MORE

Signature Science Interviewed for RAND AI Safety Paper

March 16, 2026 • Last year, Signature Science AI Biosafety Lead Dr. Danielle LeSassier was interviewed as part of a multi-institutional study led by RAND into the state of Human Uplift Studies for informing AI Safety. As providers in this space, … MORE

Horizon Newsletter – February 2026

We’re gearing up for another ASCLD Symposium and are excited to be part of 2026’s packed agenda! We’re hosting two plenary talks and one deep dive session. Scroll for a preview of SigSci Forensics on the agenda. Dates & Times TBA! View … MORE

SigSci Products

For detailed information on K9 training aids or laboratory proficiency testing, visit our product websites by clicking the appropriate link below.

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Photo of a technician working in a lab with the Text "Proficiency Testing" and a clickable link reading "LEARN MORE"