About Signature Science
We serve government and commercial clients through a wide array of technical offerings that combine scientific rigor with proven quality assurance. Our expertise enhances the credibility and defensibility of government programs that provide for our national and homeland security.

We Solve Problems Using Applied Science and Technology
Across many disciplines, our project teams are addressing some of the toughest challenges facing our nation and communities.
Join Our Team
We’re hiring

A Compelling Work Environment and Culture
Signature Science employees benefit from a compelling work environment and corporate culture that are shaped by our pursuit of scientific innovation and service to our clients’ national security, criminal justice, and public health missions.

Tackling the Toughest Scientific Problems
We bring together the brightest minds from across the scientific disciplines to apply high-quality analysis and technical skills to meet national security and law enforcement challenges. Check our current openings to see where you fit.
News
Here’s what’s happening at Signature Science lately.
American Society of Crime Laboratory Directors (ASCLD) award recognizes exemplary method validation benefitting the forensic science casework practitioners. AUSTIN, TEXAS – May 18, 2023 – Signature Science, LLC is pleased to announce that the Forensic Research Committee of the American Society … MORE
Abstract Regulation of research on microbes that cause disease in humans has historically been focused on taxonomic lists of ‘bad bugs’. However, given our increased knowledge of these pathogens through inexpensive genome sequencing, 5 decades of research in microbial pathogenesis, and the … MORE
HORIZON Newsletter – April 2023
In October CAG staff completed our Developmental Validation of the Illumina® Infinium Assay Using the Global Screening Array (GSA) on the iScan System for use in Forensic Laboratories. The study was performed in accordance with the Scientific Working Group on DNA Analysis Methods Validation … MORE