Diagram of a ball-and-stick model. Text reads "Relationship Inference Paper Published; Featured in Forensic Genomics".

Paper Published in “Forensic Genomics”: Relationship Inference with Low-Coverage Whole Genome Sequencing on Forensic Samples

Abstract Background: Single nucleotide polymorphism (SNP)-based kinship analysis is now a cornerstone of modern forensic genomics. Imputation can be used to augment genome-wide SNP data from low-coverage whole-genome sequencing (LCWGS). The impact of imputation after LCWGS on genotyping error and its subsequent impact on kinship analysis are unknown. Methods: We assessed the... MORE
Thumbnail of the front and back of the CEAT - Covid-19 Exposure Assessment Tool. Text reads "CEAT Tool Paper Published"
October 4, 2022

Paper Published in “Science Advances”: COVID-19 Exposure Assessment Tool (CEAT): Exposure quantification based on ventilation,...

Abstract The coronavirus disease 2019 (COVID-19) Exposure Assessment Tool (CEAT) allows users to compare respiratory relative risk to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) for various scenarios, providing understanding of how combinations of protective measures affect risk. CEAT incorporates mechanistic, stochastic, and epidemiological factors including the (i) emission rate... MORE
Stylized DNA helix. Text reads "Sequence Screening - Training for Bioengineers. BioMADE logo.
September 26, 2022

BioMADE Selects Signature Science-led Team to Develop Biosecurity Sequence Screening Training Course for Bioengineers

SeqScreen training course will support BioMADE’s Education & Workforce Development initiative. AUSTIN, TEXAS – Sept. 27, 2022 –Advanced bioengineering technologies offer enormous potential for creating cost-effective solutions across industries, but there is little existing guidance to avoid causing inadvertent harm to humans, livestock, crops, or the environment, or “bioerror.” As... MORE
Illustration of connected people icons in front of a cityscape. Text reads "Kinship Analysis"
September 13, 2022

SigSci Scientists Co-Author Study Published in “Frontiers in Genetics”

Abstract Technological advances in sequencing and single nucleotide polymorphism (SNP) genotyping microarray technology have facilitated advances in forensic analysis beyond short tandem repeat (STR) profiling, enabling the identification of unknown DNA samples and distant relationships. Forensic genetic genealogy (FGG) has facilitated the identification of distant relatives of both unidentified remains... MORE
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August 9, 2022

Automated Infectious Disease Forecasting: Use-cases and Practical Considerations for Pipeline Implementation

Abstract: Real-time forecasting of disease outbreaks requires standardized outputs generated in a timely manner. Development of pipelines to automate infectious disease forecasts can ensure that parameterization and software dependencies are common to any execution of the forecasting code. Here we present our implementation of an automated cloud computing pipeline to... MORE
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August 4, 2022

HORIZON Newsletter – August 2022

The Center for Advanced Genomics hits the road in August! We're headed to scientific conferences and training symposia across the country. Catch up with us at: IHIA | New Orleans, LA | August 7-9CHIA | Las Vegas, NV | August 23-26ISFG | Washington, DC | August 29- Sept. 2 Can... MORE
Image of a world map and virus cells.
July 17, 2022

FluFIVE: Publicly Hosted Flu Communication dashboard 

The Flu Forecasting Interpretation Visualization and Evaluation (FluFIVE) web application provides a user-friendly interface to explore probabilistic near-term forecasts of incident influenza hospitalizations in the United States. The source of forecasts is the CDC FluSight initiative, which since 2013 has served as a consortium to coordinate influenza forecasting efforts in the United States. FluFIVE provides forecast... MORE