February 10, 2026

New Preprint: Predicting Neutron Radiation Exposure Characteristics from an in vitro Human Skin Model Using RNA-seq

Abstract: Accurate assessment of low-dose neutron radiation exposure remains a central challenge in biodosimetry, particularly for applications requiring non-invasive sample types such as skin. Here, we characterized the transcriptional response of a three-dimensional in vitro human skin model (EpiDermFT) to neutron irradiation at doses up to 0.75 Gy, measured from pre-exposure through... MORE

Dr. Ben H. Thacker Joins Signature Science’s Managers Committee

Thacker serves as Chief Operating Officer of Southwest Research Institute. AUSTIN, TX - February 10, 2026 - Signature Science, LLC is pleased to announce the addition of Dr. Ben H. Thacker, P.E. to its Managers Committee following his appointment as Southwest Research Institute's Chief Operating Officer. Dr. Thacker brings nearly... MORE
January 5, 2026

Published in “Applied Biosafety”: Inter-tool Analysis of a NIST Dataset for Assessing Baseline Nucleic Acid Sequence...

Abstract: Introduction: Nucleic acid synthesis is a dual-use technology that can benefit fields such as biology, medicine, and information storage. However, synthetic nucleic acids could also potentially be used negligently and ultimately cause harm, or be used with malicious intent to cause harm. Thus, this technology needs to be appropriately safeguarded.... MORE
November 13, 2025

Horizon Newsletter – November 2025

Collaboration Leads to a Breakthrough in a Case That's Close to Home After over 30 years, breakthroughs in forensic science have led investigators to identify a person of interest in the 1991 murders of four young Austin-area girls; Eliza Thomas, Amy Ayers, and sisters Jennifer Harbison and Sarah Harbison. Announced... MORE
Viruses swirl into an electrified sensor
October 22, 2025

Signature Science Membership on ARPA-H BREATHE Program Team Announced

October 22, 2025 • A press release issued by The University of Virginia Biocomplexity Institute announced that the Advanced Research Projects Agency for Health (ARPA-H) has awarded a contract for up to $40 million through its Bioaerosol Risk Assessment interVention Engineering (BRAVE) program to a multidisciplinary, multi-institutional team led by Linsey... MORE
SIlhouette of a man with a dna helix in front
October 7, 2025

Authorized Statement on the Yogurt Shop Murders Investigation  

October 07, 2025 - After over 30 years, breakthroughs in forensic science have led investigators to identify a person of interest in the 1991 murders of four young Austin-area girls; Eliza Thomas, Amy Ayers, and sisters Jennifer Harbison and Sarah Harbison. Announced at a media briefing held by the City... MORE
September 12, 2025

PLANES: Plausibility Analysis of Epidemiological Signals – Webinar Now Available

From 2023-2024, CSTE partnered with several academic and industry groups to develop analytic tools for public health outbreak response. In August, 2024, Signature Science's VP Nagraj delivered a presentation as part of a CTSE-hosted webinar series on the PLANES approach and rplanes software developed through this collaboration. Register to watch... MORE
Close up on a raised hand in a classroom setting
July 18, 2025

Horizon Newsletter – July 2025

We’re excited to launch our new dedicated forensics website designed to make working with Signature Science easier and more efficient than ever before!  The new website features: Comprehensive Forensic DNA Testing Services - In-depth information on our full suite of forensic DNA testing capabilities Streamlined Communication - Simplified case submission and contact forms... MORE
Image of two women smiling. Text reads 2025 SigSci Interns
July 8, 2025

Our Interns’ Summer with SigSci Forensics

Each summer, Signature Science, LLC welcomes at least one intern to assist with research in our Center for Advanced Genomics (CAG). The research and validations performed at the CAG are shared with the forensic community in the form of open-source software, accessible publications, and conference workshops and presentations, and support... MORE