unraveling ball of rope on red background

MixDeR: A SNP Mixture Deconvolution Workflow for Forensic Genetic Genealogy

Abstract: The generation of forensic DNA profiles consisting of single nucleotide polymorphisms (SNPs) is now being facilitated by wider adoption of next-generation sequencing (NGS) methods in casework laboratories. At the same time, and in part because of this advance, there is an intense focus on the generation of SNP profiles... MORE
Empty jury bench

HORIZON Newsletter – August 2024

How are the words we use when delivering expert witness testimony understood by the average member of a jury? What impact might television shows depicting the criminal justice system and 24/7 access to news reporting have on the average jury member? And, how do we effectively communicate the science behind... MORE
universal RNA sequencing: Workflow Development

Unbiased metagenomic detection of RNA viruses for rapid identification of viral pathogens in clinical samples:...

Abstract: Unbiased long read sequencing approaches for clinical metagenomic sample analysis holds enormous potential for pathogen detection, including improved detection of unknown, novel or emerging viruses. However, the rapid rate of development in nanopore sequencing and library preparation methods complicates the process of selecting a standardized method for unbiased RNA... MORE

HORIZON Newsletter – April 2024

Signature Science is excited to be able to offer our lowest pricing for your cold case sample processing using Kintelligence!  From now until September 30, you can capitalize on our volume pricing, even if you have one or a just a few samples to process. Been holding onto a sample... MORE
aerosol cloud in pnk purple and blue. new IARPA Chemical Program Underway - Picard

IARPA Announces PICARD Program Kickoff

February 23, 2024 • An article posted to Intelligence Community News detailed the announcement from the Intelligence Advanced Research Projects Activity (IARPA) of the Pursuing Intelligent Complex Aerosols for Rapid Detection (PICARD) Project kickoff, which took place on February 21, 2024. Signature Science is a proud member of the project team. From the... MORE

Inaugural CAG Symposium Fosters Deeper Understanding of Key FIGG Topics

Roundtable discussions offered small groups the opportunity to discuss their challenges in the space of FIGG and offer solutions In recent years, Forensic Investigative Genetic Genealogy (FIGG) has become a primary focus of large forensic conferences as laboratories explore the adoption of the associated technologies and workflows, law enforcement officials... MORE