About Signature Science

We serve government and commercial clients through a wide array of technical offerings that combine scientific rigor with proven quality assurance. Our expertise enhances the credibility and defensibility of government programs that provide for our national and homeland security.

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We Solve Problems Using Applied Science and Technology

Across many disciplines, our project teams are addressing some of the toughest challenges facing our nation and communities.

Join Our Team

We’re hiring

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A Compelling Work Environment and Culture

Signature Science employees benefit from a compelling work environment and corporate culture that are shaped by our pursuit of scientific innovation and service to our clients’ national security, criminal justice, and public health missions.

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Tackling the Toughest Scientific Problems

We bring together the brightest minds from across the scientific disciplines to apply high-quality analysis and technical skills to meet national security and law enforcement challenges. Check our current openings to see where you fit.


Here’s what’s happening at Signature Science lately.

SigSCi Joins UT on DARPA B-SURE Program - Risk Evaluation: Biomanufacturing in Space

Signature Science Membership on University of Texas’ DARPA B-SURE Program Team Announced

March 17, 2023 • An article posted to Homeland Preparedness News announced the University-led teams participating in the DARPA B-SURE Program. Signature Science is proud to join the University of Washington and the University of Wisconsin-Madison on The University of … MORE

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Houston Forensic Science Center Selects Austin-Based Signature Science for Forensic DNA Casework Service

Award continues federally funded sexual assault kit backlog reduction effort AUSTIN, TEXAS – March 7, 2023 – Signature Science, LLC was awarded an 18-month, $1,108,934 contract from the Houston Forensic Science Center (HFSC) to perform forensic screening and DNA analysis of … MORE

Signature Science proud to Participate in SWRI Anniversary. Image of blurred traffic in front of SwRI front gate

Celebrating with SwRI – Annual Meeting Makes News

February 28, 2023  • Southwest Research Institute (SwRI), together with Advisory Trustees, Board of Directors and special guests, held its 75th Annual Meeting at SwRI’s headquarters in San Antonio. The Institute’s press release covering the event was picked up by … MORE

SigSci Products

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