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Image of several fever line charts superimposed on shapes and a grid.

Evaluation of FluSight influenza forecasting in the 2021–22 and 2022–23 seasons with a new target...

Abstract: Accurate forecasts can enable more effective public health responses during seasonal influenza epidemics. For the 2021–22 and 2022–23 influenza seasons, 26 forecasting teams provided national and jurisdiction-specific probabilistic predictions of weekly confirmed influenza hospital admissions for one-to-four weeks ahead. Forecast skill is evaluated using the Weighted Interval Score (WIS),... MORE
Image of blurred people in front of floating virus cells.

Containerized Model Engines for Operational Disease Forecasting

Abstract: Operational infectious disease modeling efforts are important to public health response before, during, and after outbreak events. Recent collaborative initiatives have demonstrated the success of hubs, which openly solicit modeling output from contributors. Automation techniques can help improve timeliness of submissions to hubs. Furthermore, we suggest that containerization approaches... MORE
Illustration of a virus cell. Text reads "Universal RNA Sequencing: Workflow Development"

Unbiased metagenomic detection of RNA viruses for rapid identification of viral pathogens in clinical samples:...

Abstract: Unbiased long read sequencing approaches for clinical metagenomic sample analysis holds enormous potential for pathogen detection, including improved detection of unknown, novel or emerging viruses. However, the rapid rate of development in nanopore sequencing and library preparation methods complicates the process of selecting a standardized method for unbiased RNA... MORE
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HORIZON Newsletter – April 2024

Signature Science is excited to be able to offer our lowest pricing for your cold case sample processing using Kintelligence!  From now until September 30, you can capitalize on our volume pricing, even if you have one or a just a few samples to process. Been holding onto a sample... MORE
Image of red aerosol cloud. Text reads "New IARPA Chemical Program Underway - Picard"

IARPA Announces PICARD Program Kickoff

February 23, 2024 • An article posted to Intelligence Community News detailed the announcement from the Intelligence Advanced Research Projects Activity (IARPA) of the Pursuing Intelligent Complex Aerosols for Rapid Detection (PICARD) Project kickoff, which took place on February 21, 2024. Signature Science is a proud member of the project team. From the... MORE
Thumbnail for the Center for Advanced Genomics Inaugural CAG Symposium in Charlottesville, Virginia

Inaugural CAG Symposium Fosters Deeper Understanding of Key FGG Topics

Roundtable discussions offered small groups the opportunity to discuss their challenges in the space of FIGG and offer solutions In recent years, Forensic Genetic Genealogy (FGG) has become a primary focus of large forensic conferences as laboratories explore the adoption of the associated technologies and workflows, law enforcement officials eagerly... MORE