In October CAG staff completed our Developmental Validation of the Illumina® Infinium Assay Using the Global Screening Array (GSA) on the iScan System for use in Forensic Laboratories. The study was performed in accordance with the Scientific Working Group on DNA Analysis Methods Validation Guidelines for DNA Analysis Methods, and was recently published in Forensic... MORE
Abstract R packages are the fundamental units of reproducible code in R, providing a mechanism for distributing user-developed code, documentation, and data. Docker is a virtualization technology that allows applications and their dependencies to be distributed and run reproducibly across platforms. The pracpac package provides an interface to create Docker... MORE
Published in “Forensic Genomics”: Developmental Validation of the Illumina Infinium Assay Using the Global Screening...
Abstract Microarray processing, which interrogates hundreds of thousands of single nucleotide polymorphisms (SNPs) across the human genome, has recently gained traction in forensics due to its use in forensic genetic genealogy, which is based on analysis using SNPs to compare distant relatives in publicly curated databases for the purposes of... MORE
March 17, 2023 • An article posted to Homeland Preparedness News announced the University-led teams participating in the DARPA B-SURE Program. Signature Science is proud to join the University of Washington and the University of Wisconsin-Madison on The University of Texas team. The team is focused on program track 3:... MORE
Houston Forensic Science Center Selects Austin-Based Signature Science for Forensic DNA Casework Service
Award continues federally funded sexual assault kit backlog reduction effort AUSTIN, TEXAS – March 7, 2023 – Signature Science, LLC was awarded an 18-month, $1,108,934 contract from the Houston Forensic Science Center (HFSC) to perform forensic screening and DNA analysis of backlogged biological evidence associated with sexual assault kits (SAKs)... MORE
February 28, 2023 • Southwest Research Institute (SwRI), together with Advisory Trustees, Board of Directors and special guests, held its 75th Annual Meeting at SwRI's headquarters in San Antonio. The Institute's press release covering the event was picked up by businesswire.com. Among the festivities and presentations detailed, the release mentions the... MORE
SeqScreen-Nano: a computational platform for rapid, in-field characterization of previously unseen pathogens: Preprint Available
Abstract The COVID-19 pandemic forever underscored the need for biosurveillance platforms capable of rapid detection of previously unseen pathogens. Oxford Nanopore Technology (ONT) couples long-read sequencing with in-field capability, opening the door to real-time, in-field biosurveillance. Though a promising technology, streaming assignment of accurate functional and taxonomic labels with nanopore... MORE
Founders Announce Establishment of the National Technology Validation and Implementation Collaborative (NTVIC) and Forensic Investigative...
In a paper published in Forensic Science International: Synergy, founders of the National Technology Validation and Implementation Collaborative (NTVIC) announced the group's formation, in addition to the formation of its first Technology Validation Working Group, the Forensic Investigative Genetic Genealogy Technology Validation Group (FIGG-TVG). Signature Science's Center for Advanced Genomics... MORE
Join the CAG in celebrating with AAFS in Orlando (Feb 13-18)! Stop by our Booth 401 - our CAG stainless steel pint glass giveaway will help you raise a toast to 75 years of The American Academy of Forensic Sciences! Fear of Missing Out? Arrange a meetup before you go. We face... MORE
Published in “Forensic Genomics”: Internal Validation of the ForenSeq® Kintelligence Kit for Application to Forensic...
Abstract Forensic Genetic Genealogy (FGG) requires high-density single nucleotide polymorphism (SNP) profiles to infer distant relationships. The ForenSeq Kintelligence kit is a recently developed method targeting 10,230 SNPs that were selected to be compatible with genetic genealogy databases, whereas avoiding medically relevant SNPs. The targeted polymerase chain reaction method is... MORE