Technical Papers and Posters | News

Synthetic DNA and biosecurity: Nuances of predicting pathogenicity and the impetus for novel computational approaches for screening oligonucleotides

A discussion of the challenges associated with screening synthetic DNA for biosecurity risk and an argument for taking steps to move beyond the classic model of taxonomic biothreat classification and ...

Signature Science team authored paper published in “BMC Infectious Diseases”

Title: Simulating Transmission of ESKAPE Pathogens Plus C. difficile in Relevant Clinical Scenarios Authors: Katharina L. Weber, Danielle S. LeSassier, Anthony D. Kappell, Kathleen Q. Schulte, Nicole Westfall, Nicolette C. ...

SigSci scientists co-author study published in "Forensic Science International: Genetics"

Title: An Algorithm for Random Match Probability Calculation from Peptide Sequences Authors: August E. Woerner,1* F. Curtis Hewitt,2 Myles W. Gardner,2 Michael A. Freitas,3,4 Kathleen Q. Schulte,2 Danielle S. LeSassier,2 ...

Next Generation Sequencing to Detect Environmental Stress

Dr. Krista Ternus presented her research at the National Environmental Monitoring Conference held August 5-9, 2019.

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Mendelian Simulation of STR Genotypes from Existing Sample Data to Create Standard Truth Pedigrees for Benchmarking New Familial Inference Methods

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Artificial Fingerprints for Reproducible Development of Touch Sample Analysis Methods

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Validating Metagenomic Analyses through Simulated Direct and Indirect Healthcare-Related Pathogen Transmission Events

Signature Science’s work was presented by Krista Ternus at the Sequencing, Finishing, and Analysis in the Future Meeting held May 21-23, 2019.

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SigSci’s Austin TX-based DNA Forensics Laboratory participated in an interlab study that demonstrated a high level of repeatability and reproducibility with STRmix™ probabilistic genotyping software.

Title: STRmix™ collaborative exercise on DNA mixture interpretation Authors: Jo-Anne Bright, Kevin Cheng, Zane Kerr, Catherine McGovern, Hannah Kelly, Tamyra R. Moretti, Michael A. Smith, Frederick R. Bieber, Bruce ...

SigSci presents poster at 2nd ASM Conference on Rapid Applied Microbial Next-Generation Sequencing and Bioinformatic Pipelines

Title: Toward Rapid Sequenced-Based Detection and Characterization of Causative Agents of Bacteremia Authors: F. Curtis Hewitt, Stephanie L. Guertin, Krista L. Ternus, Kathleen Schulte, and Dana R. Kadavy Summary: High-throughput ...

Paper authored by SigSci scientists published in peer-reviewed journal "Analytical Chemistry"

Title: A Systematic Method for the Targeted Discovery of Chemical Attribution Signatures – Application to Isopropyl Bicyclophosphate Production Authors: Carolyn L. Mazzitelli, Michael A. Re, Melissa A. Reaves, Carlos ...

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Synthetic DNA and biosecurity: Nuances of predicting pathogenicity and the impetus for novel computational approaches for screening oligonucleotides

Signature Science team authored paper published in “BMC Infectious Diseases”

SigSci scientists co-author study published in "Forensic Science International: Genetics"

Next Generation Sequencing to Detect Environmental Stress

Mendelian Simulation of STR Genotypes from Existing Sample Data to Create Standard Truth Pedigrees for Benchmarking New Familial Inference Methods

Artificial Fingerprints for Reproducible Development of Touch Sample Analysis Methods

Validating Metagenomic Analyses through Simulated Direct and Indirect Healthcare-Related Pathogen Transmission Events

SigSci’s Austin TX-based DNA Forensics Laboratory participated in an interlab study that demonstrated a high level of repeatability and reproducibility with STRmix™ probabilistic genotyping software.

SigSci presents poster at 2nd ASM Conference on Rapid Applied Microbial Next-Generation Sequencing and Bioinformatic Pipelines

Paper authored by SigSci scientists published in peer-reviewed journal "Analytical Chemistry"

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Recent Press

Signature Science Receives Contract from City of Corpus Christi to Provide Sexual Assault Kit Testing Services

Signature Science receives contract from Houston Forensic Science Center to provide DNA forensic casework services

Synthetic DNA and biosecurity: Nuances of predicting pathogenicity and the impetus for novel computational approaches for screening oligonucleotides

New Methods, Same Motives: the IED Threat Requires a Resolute Response

Signature Science team authored paper published in “BMC Infectious Diseases”