At Signature Science, we understand that unlocking the full value of statistical approaches to scientific and technical endeavors requires integration of statistical thinking throughout the effort, starting from the very beginning. For that reason, we support National Security programs using fully integrated technical teams where our statisticians work side-by-side with subject matter experts in chemistry, biology, or other relevant technical disciplines to define the problem, develop the technical approach, and deliver a solution. By integrating statistical thinking into the process from the outset, we ensure we are asking the right questions, collecting a sufficient amount of the right types of data, and bringing appropriate data analysis methods to bear on the problem.